MicroMGx, Inc., a life sciences company dedicated to making high-throughput natural product discovery achievable, today announced an expanded agreement focused on accelerating natural products discovery with pure-play global agriculture company Corteva Agriscience. Read announcement: https://www.micromgx.com/micromgx-partners-with-corteva-agriscience-to-expand-use-of-natural-products-discovery-for-crop-protection/
Glossary of Terms
Actinobacteria is a phylum of Gram-positive bacteria with high guanine and cytosine content in their DNA. Although understood primarily as soil bacteria, they might be more abundant in freshwaters. Considered to be one of the most prolific producers of natural products.
Bacteria are single celled microbes. The cell structure is simpler than that of other organisms as there is no nucleus or membrane bound organelles. Instead their control centre containing the genetic information is contained in a single loop of DNA.
A biological system is a complex network of biologically relevant entities. As biological organization spans several scales, examples of biological systems are populations of organisms, or on the organ- and tissue scale in mammals and other animals, the circulatory system, the respiratory system, the nervous system, etc.
On the micro- to the nanoscopic scale, examples of biological systems are cells, organelles, macromolecular complexes and regulatory pathways.
A compound is a substance formed when two or more chemical elements are chemically bonded together.
High-performance liquid chromatography (HPLC; formerly referred to as high-pressure liquid chromatography), is a technique in analytical chemistry used to separate, identify, and quantify each component in a mixture. It relies on pumps to pass a pressurized liquid solvent containing the sample mixture through a column filled with a solid adsorbent material.
Mass Spectrometry (MS) is an analytical chemistry technique that helps identify the amount and type of chemicals present in a sample by measuring the mass-to-charge ratio and abundance of gas-phase ions.
Metabolites are the intermediates and products of metabolism. The term metabolite is usually restricted to small molecules. Metabolites have various functions, including fuel, structure, signaling, stimulatory and inhibitory effects on enzymes, catalytic activity of their own (usually as a cofactor to an enzyme), defense, and interactions with other organisms (e.g. pigments, odorants, and pheromones).
A natural products discovery platform that fuses metabolomics and genomics to increase the throughput of discovery.
A group of natural products that exhibit structural similarity and are likely related through biosynthesis.
A natural product is a chemical compound or substance produced by a living organism—that is, found in nature.
MicroMGx’s innovative software for navigating the complexity of natural product chemical space.
A strain is a genetic variant or subtype of a micro-organism (e.g., virus or bacterium or fungus).