We are proud to announce that Richard Baltz has joined MicroMGx as a Scientific Advisor. Dr. Baltz is a both a pioneer and thought leader in #naturalproducts discovery. He led the Eli Lilly Molecular Genetics department and helped establish Lilly as a world leader in genetic engineering of industrial actinomycetes. Later, he worked with Cubist Pharmaceuticals to launch the last new antibiotic – Cubicin. Richard’s knowledge of microbial strain collections is unsurpassed, knowledge that will be quite useful as we continue to build the world’s largest metabologenomics library. Dr. Baltz was recently interviewed about how the world can solve the Antimicrobial Resistance problem. You can view that interview here.
We will continue to add world-class Science/Industry Advisors to MicroMGx. Their objectivity, experience, expertise, and networks will increase the quality of our MGX Library, the speed of our commercialization, and the strength of our overall strategy.
Actinobacteria is a phylum of Gram-positive bacteria with high guanine and cytosine content in their DNA. Although understood primarily as soil bacteria, they might be more abundant in freshwaters. Considered to be one of the most prolific producers of natural products.
Bacteria are single celled microbes. The cell structure is simpler than that of other organisms as there is no nucleus or membrane bound organelles. Instead their control centre containing the genetic information is contained in a single loop of DNA.
A biological system is a complex network of biologically relevant entities. As biological organization spans several scales, examples of biological systems are populations of organisms, or on the organ- and tissue scale in mammals and other animals, the circulatory system, the respiratory system, the nervous system, etc.
On the micro- to the nanoscopic scale, examples of biological systems are cells, organelles, macromolecular complexes and regulatory pathways.
High-performance liquid chromatography (HPLC; formerly referred to as high-pressure liquid chromatography), is a technique in analytical chemistry used to separate, identify, and quantify each component in a mixture. It relies on pumps to pass a pressurized liquid solvent containing the sample mixture through a column filled with a solid adsorbent material.
Mass Spectrometry (MS) is an analytical chemistry technique that helps identify the amount and type of chemicals present in a sample by measuring the mass-to-charge ratio and abundance of gas-phase ions.
Metabolites are the intermediates and products of metabolism. The term metabolite is usually restricted to small molecules. Metabolites have various functions, including fuel, structure, signaling, stimulatory and inhibitory effects on enzymes, catalytic activity of their own (usually as a cofactor to an enzyme), defense, and interactions with other organisms (e.g. pigments, odorants, and pheromones).